Oral Presentation 26th Annual Lorne Proteomics Symposium 2021

Blink of an Eye (#40)

Sarah Alexander 1 , Tom Covey 1
  1. SCIEX, Mount Waverly, VIC, Australia

Echo MS is a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray ionization (ESI) MS that creates a transformative system enabling high-speed sampling and label-free analysis. The technology delivers nanoliter droplets in a touchless manner with high speed, precision and accuracy; subsequent sample dilution within the OPI, in concert with the capabilities of modern ESI-MS, eliminates the laborious sample preparation and method development required in current approaches. This novel new platform has already been applied to a variety of experiments, including high-throughput (HT) pharmacology screening, label-free in situ enzyme kinetics, in vitro and in vivo adsorption, distribution, metabolism, elimination, pharmacokinetic (PK) and biomarker analysis, and HT parallel medicinal chemistry. I will present some of the latest applications and developments for this game changing Technology.

Why a Blink of an Eye?

A Blink of an eye is about 400-500 milliseconds depending on your source of information.  A baker’s dozen is 13 and this system can  analyse  6-12 samples in the time it takes for one or two  eye blinks!! 

 

This presentation is sponsored by

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